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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
24.55
Human Site:
Y866
Identified Species:
33.75
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
Y866
L
E
D
E
N
N
R
Y
Q
V
E
L
E
N
L
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
Y866
L
E
D
E
N
N
R
Y
Q
V
E
L
E
N
L
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
Y865
L
E
D
E
N
N
R
Y
Q
V
E
L
E
N
L
Dog
Lupus familis
XP_533766
1089
122761
Y863
L
E
D
E
N
N
R
Y
Q
V
E
L
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
Y864
L
E
D
E
N
S
R
Y
Q
V
E
L
E
N
I
Rat
Rattus norvegicus
NP_446123
1093
121882
Y866
L
E
D
E
N
S
R
Y
Q
V
E
L
E
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
C873
L
K
D
E
N
N
R
C
Q
V
E
L
E
N
L
Chicken
Gallus gallus
O42184
1433
161009
K1023
E
T
S
E
M
I
T
K
H
D
A
D
I
K
G
Frog
Xenopus laevis
Q5PQ23
649
75475
E436
Q
L
V
G
N
D
S
E
L
A
K
A
L
S
S
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
E901
L
E
D
D
L
S
R
E
R
V
E
L
E
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
Q719
L
E
Q
L
C
Q
R
Q
K
E
E
E
E
Q
R
Honey Bee
Apis mellifera
XP_394037
1326
150590
T984
T
K
K
I
L
A
A
T
E
V
E
L
K
E
A
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
D1492
D
L
R
N
T
S
T
D
L
F
K
A
K
N
A
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
D946
L
E
E
S
K
I
R
D
F
S
H
M
E
N
Q
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
I762
E
E
I
Q
D
A
L
I
N
R
E
L
L
Q
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
H743
I
R
E
L
R
R
K
H
K
Q
E
L
Q
E
V
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
E494
N
S
M
E
G
N
I
E
D
E
W
T
L
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
86.6
6.6
6.6
66.6
N.A.
33.3
20
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
26.6
86.6
N.A.
40
40
26.6
46.6
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
6
0
0
6
6
12
0
0
12
% A
% Cys:
0
0
0
0
6
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
6
0
48
6
6
6
0
12
6
6
0
6
0
0
0
% D
% Glu:
12
59
12
53
0
0
0
18
6
12
71
6
59
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% F
% Gly:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
6
6
0
6
0
0
0
0
% H
% Ile:
6
0
6
6
0
12
6
6
0
0
0
0
6
0
6
% I
% Lys:
0
12
6
0
6
0
6
6
12
0
12
0
12
6
0
% K
% Leu:
59
12
0
12
12
0
6
0
12
0
0
65
18
0
42
% L
% Met:
0
0
6
0
6
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
6
0
0
6
48
36
0
0
6
0
0
0
0
59
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% P
% Gln:
6
0
6
6
0
6
0
6
42
6
0
0
6
12
18
% Q
% Arg:
0
6
6
0
6
6
59
0
6
6
0
0
0
0
6
% R
% Ser:
0
6
6
6
0
24
6
0
0
6
0
0
0
6
6
% S
% Thr:
6
6
0
0
6
0
12
6
0
0
0
6
0
0
0
% T
% Val:
0
0
6
0
0
0
0
0
0
53
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _